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The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization
During preimplantation development, contractile forces generated at the apical cortex segregate cells into inner and outer positions of the embryo, establishing the inner cell mass (ICM) and trophectoderm. To which extent these forces influence ICM-trophectoderm fate remains unresolved. Here, we fou...
Autores principales: | Skory, Robin M., Moverley, Adam A., Ardestani, Goli, Alvarez, Yanina, Domingo-Muelas, Ana, Pomp, Oz, Hernandez, Blake, Tetlak, Piotr, Bissiere, Stephanie, Stern, Claudio D., Sakkas, Denny, Plachta, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10226985/ https://www.ncbi.nlm.nih.gov/pubmed/37248263 http://dx.doi.org/10.1038/s41467-023-38770-5 |
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