Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally

People are widely exposed to polycyclic aromatic hydrocarbons, like benzo[a]pyrene (BaP). Prior studies showed that prenatal exposure to BaP depletes germ cells in ovaries, causing earlier onset of ovarian senescence post-natally; developing testes were affected at higher doses than ovaries. Our pri...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Jinhwan, Shioda, Toshihiro, Malott, Kelli F., Shioda, Keiko, Odajima, Junko, Leon Parada, Kathleen N., Nguyen, Julie, Getze, Samantha, Lee, Melody, Nguyen, Jonathon, Reshel Blakeley, Samantha, Trinh, Vienna, Truong, Hong-An, Luderer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227008/
https://www.ncbi.nlm.nih.gov/pubmed/37248279
http://dx.doi.org/10.1038/s41598-023-35494-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227008/
https://www.ncbi.nlm.nih.gov/pubmed/37248279
http://dx.doi.org/10.1038/s41598-023-35494-w

Ejemplares similares