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Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally

People are widely exposed to polycyclic aromatic hydrocarbons, like benzo[a]pyrene (BaP). Prior studies showed that prenatal exposure to BaP depletes germ cells in ovaries, causing earlier onset of ovarian senescence post-natally; developing testes were affected at higher doses than ovaries. Our pri...

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Detalles Bibliográficos
Autores principales:	Lim, Jinhwan, Shioda, Toshihiro, Malott, Kelli F., Shioda, Keiko, Odajima, Junko, Leon Parada, Kathleen N., Nguyen, Julie, Getze, Samantha, Lee, Melody, Nguyen, Jonathon, Reshel Blakeley, Samantha, Trinh, Vienna, Truong, Hong-An, Luderer, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227008/ https://www.ncbi.nlm.nih.gov/pubmed/37248279 http://dx.doi.org/10.1038/s41598-023-35494-w

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