Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health

Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling maturation of the endo-lysosomal network. Retromer dysfunction, which is linked to neurodegenerative disorders including Parkinson’s and Alzheimer’s diseases, manifests in com...

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Detalles Bibliográficos
Autores principales: Daly, James L., Danson, Chris M., Lewis, Philip A., Zhao, Lu, Riccardo, Sara, Di Filippo, Lucio, Cacchiarelli, Davide, Lee, Daehoon, Cross, Stephen J., Heesom, Kate J., Xiong, Wen-Cheng, Ballabio, Andrea, Edgar, James R., Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227043/
https://www.ncbi.nlm.nih.gov/pubmed/37248224
http://dx.doi.org/10.1038/s41467-023-38719-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227043/
https://www.ncbi.nlm.nih.gov/pubmed/37248224
http://dx.doi.org/10.1038/s41467-023-38719-8

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