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Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice

Pharmacological treatments for advanced hepatocellular carcinoma (HCC) have a partial efficacy. Augmented Na(+) content and water retention are observed in human cancers and offer unexplored targets for anticancer therapies. Na(+) levels are evaluated upon treatments with the antibiotic cation ionop...

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Detalles Bibliográficos
Autores principales: Clemente, Nausicaa, Baroni, Simona, Fiorilla, Simone, Tasso, Francesco, Reano, Simone, Borsotti, Chiara, Ruggiero, Maria Rosaria, Alchera, Elisa, Corrazzari, Marco, Walker, Gillian, Follenzi, Antonia, Crich, Simonetta Geninatti, Carini, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227045/
https://www.ncbi.nlm.nih.gov/pubmed/37248274
http://dx.doi.org/10.1038/s42003-023-04946-4