Cargando…
Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice
Pharmacological treatments for advanced hepatocellular carcinoma (HCC) have a partial efficacy. Augmented Na(+) content and water retention are observed in human cancers and offer unexplored targets for anticancer therapies. Na(+) levels are evaluated upon treatments with the antibiotic cation ionop...
Autores principales: | Clemente, Nausicaa, Baroni, Simona, Fiorilla, Simone, Tasso, Francesco, Reano, Simone, Borsotti, Chiara, Ruggiero, Maria Rosaria, Alchera, Elisa, Corrazzari, Marco, Walker, Gillian, Follenzi, Antonia, Crich, Simonetta Geninatti, Carini, Rita |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227045/ https://www.ncbi.nlm.nih.gov/pubmed/37248274 http://dx.doi.org/10.1038/s42003-023-04946-4 |
Ejemplares similares
-
Evidence for the Role of Intracellular Water Lifetime as a Tumour Biomarker Obtained by In Vivo Field‐Cycling Relaxometry
por: Ruggiero, Maria Rosaria, et al.
Publicado: (2018) -
DUSP12 acts as a novel endogenous protective signal against hepatic ischemia–reperfusion damage by inhibiting ASK1 pathway
por: Boldorini, Renzo, et al.
Publicado: (2021) -
Intracellular Water Lifetime as a Tumor Biomarker to Monitor Doxorubicin Treatment via FFC-Relaxometry in a Breast Cancer Model
por: Ruggiero, Maria Rosaria, et al.
Publicado: (2021) -
Ischemia/Reperfusion Injury of Fatty Liver Is Protected by A2AR and Exacerbated by A1R Stimulation through Opposite Effects on ASK1 Activation
por: Alchera, Elisa, et al.
Publicado: (2021) -
Pharmacological Preconditioning by Adenosine A2a Receptor Stimulation: Features of the Protected Liver Cell Phenotype
por: Alchera, Elisa, et al.
Publicado: (2015)