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Cochlear transcript diversity and its role in auditory functions implied by an otoferlin short isoform

Isoforms of a gene may contribute to diverse biological functions. In the cochlea, the repertoire of alternative isoforms remains unexplored. We integrated single-cell short-read and long-read RNA sequencing techniques and identified 236,012 transcripts, 126,612 of which were unannotated in the GENC...

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Detalles Bibliográficos
Autores principales: Liu, Huihui, Liu, Hongchao, Wang, Longhao, Song, Lei, Jiang, Guixian, Lu, Qing, Yang, Tao, Peng, Hu, Cai, Ruijie, Zhao, Xingle, Zhao, Ting, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227054/
https://www.ncbi.nlm.nih.gov/pubmed/37248244
http://dx.doi.org/10.1038/s41467-023-38621-3