Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo

To date, no herpesvirus has been shown to latently persist in fibroblastic cells. Here, we show that murine cytomegalovirus, a β-herpesvirus, persists for the long term and across organs in PDGFRα-positive fibroblastic cells, with similar or higher genome loads than in the previously known sites of...

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Detalles Bibliográficos
Autores principales: Sitnik, Katarzyna M., Krstanović, Fran, Gödecke, Natascha, Rand, Ulfert, Kubsch, Tobias, Maaß, Henrike, Kim, Yeonsu, Brizić, Ilija, Čičin-Šain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227055/
https://www.ncbi.nlm.nih.gov/pubmed/37248241
http://dx.doi.org/10.1038/s41467-023-38449-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227055/
https://www.ncbi.nlm.nih.gov/pubmed/37248241
http://dx.doi.org/10.1038/s41467-023-38449-x

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