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Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo
To date, no herpesvirus has been shown to latently persist in fibroblastic cells. Here, we show that murine cytomegalovirus, a β-herpesvirus, persists for the long term and across organs in PDGFRα-positive fibroblastic cells, with similar or higher genome loads than in the previously known sites of...
Autores principales: | Sitnik, Katarzyna M., Krstanović, Fran, Gödecke, Natascha, Rand, Ulfert, Kubsch, Tobias, Maaß, Henrike, Kim, Yeonsu, Brizić, Ilija, Čičin-Šain, Luka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227055/ https://www.ncbi.nlm.nih.gov/pubmed/37248241 http://dx.doi.org/10.1038/s41467-023-38449-x |
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