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A specific dispiropiperazine derivative that arrests cell cycle, induces apoptosis, necrosis and DNA damage

Dispiropiperazine compounds are a class of molecules known to confer biological activity, but those that have been studied as cell cycle regulators are few in number. Here, we report the characterization and synthesis of two dispiropiperazine derivatives: the previously synthesized spiro[2′,3]-bis(a...

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Detalles Bibliográficos
Autores principales: Liu, Victor P., Li, Wai-Ming, Lofroth, Jack, Zeb, Mehreen, Patrick, Brian O., Bott, Tina M., Lee, Chow H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227070/
https://www.ncbi.nlm.nih.gov/pubmed/37248333
http://dx.doi.org/10.1038/s41598-023-35927-6