A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma

BACKGROUND: Pegylated arginine deiminase (ADI-PEG20; pegargiminase) depletes arginine and improves survival outcomes for patients with argininosuccinate synthetase 1 (ASS1)-deficient malignant pleural mesothelioma (MPM). Optimisation of ADI-PEG20-based therapy will require a deeper understanding of...

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Detalles Bibliográficos
Autores principales: Phillips, Melissa M., Pavlyk, Iuliia, Allen, Michael, Ghazaly, Essam, Cutts, Rosalind, Carpentier, Josephine, Berry, Joe Scott, Nattress, Callum, Feng, Shenghui, Hallden, Gunnel, Chelala, Claude, Bomalaski, John, Steele, Jeremy, Sheaff, Michael, Balkwill, Frances, Szlosarek, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227144/
https://www.ncbi.nlm.nih.gov/pubmed/37010783
http://dx.doi.org/10.1007/s43440-023-00480-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227144/
https://www.ncbi.nlm.nih.gov/pubmed/37010783
http://dx.doi.org/10.1007/s43440-023-00480-6

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