Delayed viral vector mediated delivery of neurotrophin-3 improves skilled hindlimb function and stability after thoracic contusion

Intramuscular injection of an Adeno-associated viral vector serotype 1 (AAV1) encoding Neurotrophin-3 (NT3) into hindlimb muscles 24 h after a severe T9 spinal level contusion in rats has been shown to induce lumbar spinal neuroplasticity, partially restore locomotive function and reduce spasms duri...

Descripción completa

Detalles Bibliográficos
Autores principales: Sydney-Smith, Jared D., Koltchev, Alice M., Moon, Lawrence D.F., Warren, Philippa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227192/
https://www.ncbi.nlm.nih.gov/pubmed/36455639
http://dx.doi.org/10.1016/j.expneurol.2022.114278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227192/
https://www.ncbi.nlm.nih.gov/pubmed/36455639
http://dx.doi.org/10.1016/j.expneurol.2022.114278

Ejemplares similares