Cargando…
Delayed viral vector mediated delivery of neurotrophin-3 improves skilled hindlimb function and stability after thoracic contusion
Intramuscular injection of an Adeno-associated viral vector serotype 1 (AAV1) encoding Neurotrophin-3 (NT3) into hindlimb muscles 24 h after a severe T9 spinal level contusion in rats has been shown to induce lumbar spinal neuroplasticity, partially restore locomotive function and reduce spasms duri...
Autores principales: | Sydney-Smith, Jared D., Koltchev, Alice M., Moon, Lawrence D.F., Warren, Philippa M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227192/ https://www.ncbi.nlm.nih.gov/pubmed/36455639 http://dx.doi.org/10.1016/j.expneurol.2022.114278 |
Ejemplares similares
-
Delayed peripheral treatment with neurotrophin-3 improves sensorimotor recovery after central nervous system injury
por: Kakanos, Sotiris G., et al.
Publicado: (2019) -
RNA sequencing dataset describing transcriptional changes in cervical dorsal root ganglia after bilateral pyramidotomy and forelimb intramuscular gene therapy with an adeno-associated viral vector encoding human neurotrophin-3
por: Kathe, Claudia, et al.
Publicado: (2018) -
Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats
por: Boyce, Vanessa S, et al.
Publicado: (2012) -
The effect of mesenchymal stem cell transplantation on the recovery of bladder and hindlimb function after spinal cord contusion in rats
por: Park, Won Beom, et al.
Publicado: (2010) -
Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector: Transduction of the CST using viral vectors
por: Hutson, Thomas H., et al.
Publicado: (2011)