Extrafollicular IgD(−)CD27(−)CXCR5(−)CD11c(−) DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19

Although therapeutic B cell depletion dramatically resolves inflammation in many diseases in which antibodies appear not to play a central role, distinct extrafollicular pathogenic B cell subsets that accumulate in disease lesions have hitherto not been identified. The circulating immunoglobulin D (...

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Detalles Bibliográficos
Autores principales: Allard-Chamard, Hugues, Kaneko, Naoki, Bertocchi, Alice, Sun, Na, Boucau, Julie, Kuo, Hsiao-Hsuan, Farmer, Jocelyn R., Perugino, Cory, Mahajan, Vinay S., Murphy, Samuel J.H., Premo, Katherine, Diefenbach, Thomas, Ghebremichael, Musie, Yuen, Grace, Kotta, Alekhya, Akman, Zafer, Lichterfeld, Mathias, Walker, Bruce D., Yu, Xu G., Moriyama, Masafumi, Maehara, Takashi, Nakamura, Seiji, Stone, John H., Padera, Robert F., Pillai, Shiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227203/
https://www.ncbi.nlm.nih.gov/pubmed/37300833
http://dx.doi.org/10.1016/j.celrep.2023.112630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227203/
https://www.ncbi.nlm.nih.gov/pubmed/37300833
http://dx.doi.org/10.1016/j.celrep.2023.112630

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