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Peptidase Inhibitor 16 Attenuates Left Ventricular Injury and Remodeling After Myocardial Infarction by Inhibiting the HDAC1‐Wnt3a‐β‐Catenin Signaling Axis

BACKGROUND: Myocardial infarction (MI) is a cardiovascular disease with high morbidity and mortality. PI16 (peptidase inhibitor 16), as a secreted protein, is highly expressed in heart diseases such as heart failure. However, the functional role of PI16 in MI is unknown. This study aimed to investig...

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Detalles Bibliográficos
Autores principales: Wang, Luyang, Du, Anning, Lu, Yan, Zhao, Yunxi, Qiu, Ming, Su, Zhenyang, Shu, Huanyu, Shen, Hui, Sun, Wei, Kong, Xiangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227313/
https://www.ncbi.nlm.nih.gov/pubmed/37158154
http://dx.doi.org/10.1161/JAHA.122.028866