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Refining the genomic determinants underlying escape from X-chromosome inactivation

X-chromosome inactivation (XCI) epigenetically silences one X chromosome in every cell in female mammals. Although the majority of X-linked genes are silenced, in humans 20% or more are able to escape inactivation and continue to be expressed. Such escape genes are important contributors to sex diff...

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Detalles Bibliográficos
Autores principales: Peeters, Samantha, Leung, Tiffany, Fornes, Oriol, Farkas, Rachelle A, Wasserman, Wyeth W, Brown, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227363/
https://www.ncbi.nlm.nih.gov/pubmed/37260510
http://dx.doi.org/10.1093/nargab/lqad052