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Refining the genomic determinants underlying escape from X-chromosome inactivation
X-chromosome inactivation (XCI) epigenetically silences one X chromosome in every cell in female mammals. Although the majority of X-linked genes are silenced, in humans 20% or more are able to escape inactivation and continue to be expressed. Such escape genes are important contributors to sex diff...
Autores principales: | Peeters, Samantha, Leung, Tiffany, Fornes, Oriol, Farkas, Rachelle A, Wasserman, Wyeth W, Brown, Carolyn J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227363/ https://www.ncbi.nlm.nih.gov/pubmed/37260510 http://dx.doi.org/10.1093/nargab/lqad052 |
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