PGM3 inhibition shows cooperative effects with erastin inducing pancreatic cancer cell death via activation of the unfolded protein response

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor patient prognosis. Remarkably, PDAC is one of the most aggressive and deadly tumor types and is notorious for its resistance to all types of treatment. PDAC resistance is frequently associated with a wide m...

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Detalles Bibliográficos
Autores principales: Zerbato, Barbara, Gobbi, Maximilian, Ludwig, Tobias, Brancato, Virginia, Pessina, Alex, Brambilla, Luca, Wegner, Andre, Chiaradonna, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227458/
https://www.ncbi.nlm.nih.gov/pubmed/37260977
http://dx.doi.org/10.3389/fonc.2023.1125855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227458/
https://www.ncbi.nlm.nih.gov/pubmed/37260977
http://dx.doi.org/10.3389/fonc.2023.1125855

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