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PGM3 inhibition shows cooperative effects with erastin inducing pancreatic cancer cell death via activation of the unfolded protein response
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor patient prognosis. Remarkably, PDAC is one of the most aggressive and deadly tumor types and is notorious for its resistance to all types of treatment. PDAC resistance is frequently associated with a wide m...
Autores principales: | Zerbato, Barbara, Gobbi, Maximilian, Ludwig, Tobias, Brancato, Virginia, Pessina, Alex, Brambilla, Luca, Wegner, Andre, Chiaradonna, Ferdinando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227458/ https://www.ncbi.nlm.nih.gov/pubmed/37260977 http://dx.doi.org/10.3389/fonc.2023.1125855 |
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