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Genetic polymorphisms influencing deferasirox pharmacokinetics, efficacy, and adverse drug reactions: a systematic review and meta-analysis

Objective: Deferasirox is an iron-chelating agent prescribed to patients with iron overload. Due to the interindividual variability of deferasirox responses reported in various populations, this study aims to determine the genetic polymorphisms that influence drug responses. Methods: A systematic se...

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Detalles Bibliográficos
Autores principales: Yampayon, Kittika, Anantachoti, Puree, Chongmelaxme, Bunchai, Yodsurang, Varalee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227503/
https://www.ncbi.nlm.nih.gov/pubmed/37261288
http://dx.doi.org/10.3389/fphar.2023.1069854