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Integrative analysis revealed the role of glucagon-like peptide-2 in improving experimental colitis in mice by inhibiting inflammatory pathways, regulating glucose metabolism, and modulating gut microbiota

INTRODUCTION: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by recurrent and remitting inflammation of the mucosa of the colon and rectum, the incidence of which is on the rise. Glucagon-like peptide-2 (GLP-2) is a newly discovered neurotrophic factor, but its efficacy and m...

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Detalles Bibliográficos
Autores principales: Li, Dongyue, Gao, Yanhong, Cui, Lanrong, Li, Yang, Ling, Hao, Tan, Xin, Xu, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227514/
https://www.ncbi.nlm.nih.gov/pubmed/37260689
http://dx.doi.org/10.3389/fmicb.2023.1174308