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Comparison of methods generating antibody-epitope conjugates for targeting cancer with virus-specific T cells

Therapeutic antibody-epitope conjugates (AECs) are promising new modalities to deliver immunogenic epitopes and redirect virus-specific T-cell activity to cancer cells. Nevertheless, many aspects of these antibody conjugates require optimization to increase their efficacy. Here we evaluated differen...

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Detalles Bibliográficos
Autores principales: van der Wulp, Willemijn, Gram, Anna M., Bleijlevens, Boris, Hagedoorn, Renate S., Araman, Can, Kim, Robbert Q., Drijfhout, Jan Wouter, Parren, Paul W. H. I., Hibbert, Richard G., Hoeben, Rob C., van Kasteren, Sander I., Schuurman, Janine, Ressing, Maaike E., Heemskerk, Mirjam H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227578/
https://www.ncbi.nlm.nih.gov/pubmed/37261346
http://dx.doi.org/10.3389/fimmu.2023.1183914