Cargando…
Troponin-I–induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle
Regulation of the crossbridge cycle that drives muscle contraction involves a reconfiguration of the troponin–tropomyosin complex on actin filaments. By comparing atomic models of troponin–tropomyosin fitted to cryo-EM structures of inhibited and Ca(2+)-activated thin filaments, we find that tropomy...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227645/ https://www.ncbi.nlm.nih.gov/pubmed/37249525 http://dx.doi.org/10.1085/jgp.202313387 |