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Amide- and bis-amide-linked highly potent and broadly active antifungal agents for the treatment of invasive fungal infections- towards the discovery of pre-clinical development candidate FC12406

Most fungal infections are common, localized to skin or mucosal surfaces and can be treated effectively with topical antifungal agents. However, while invasive fungal infections (IFIs) are uncommon, they are very difficult to control medically, and are associated with high mortality rates. We have p...

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Detalles Bibliográficos
Autores principales: Baugh, Simon D. P., Chaly, Anna, Weaver, Damian G., Whitman, David B., Pelletier, Jeffrey C., Bian, Haiyan, Freeman, Katie B., Reitz, Allen B., Scott, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227796/
https://www.ncbi.nlm.nih.gov/pubmed/37362318
http://dx.doi.org/10.1007/s00044-023-03083-1