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Amide- and bis-amide-linked highly potent and broadly active antifungal agents for the treatment of invasive fungal infections- towards the discovery of pre-clinical development candidate FC12406
Most fungal infections are common, localized to skin or mucosal surfaces and can be treated effectively with topical antifungal agents. However, while invasive fungal infections (IFIs) are uncommon, they are very difficult to control medically, and are associated with high mortality rates. We have p...
Autores principales: | Baugh, Simon D. P., Chaly, Anna, Weaver, Damian G., Whitman, David B., Pelletier, Jeffrey C., Bian, Haiyan, Freeman, Katie B., Reitz, Allen B., Scott, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227796/ https://www.ncbi.nlm.nih.gov/pubmed/37362318 http://dx.doi.org/10.1007/s00044-023-03083-1 |
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