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Amplifying gene expression with RNA-targeted therapeutics

Many diseases are caused by insufficient expression of mutated genes and would benefit from increased expression of the corresponding protein. However, in drug development, it has been historically easier to develop drugs with inhibitory or antagonistic effects. Protein replacement and gene therapy...

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Detalles Bibliográficos
Autores principales: Khorkova, Olga, Stahl, Jack, Joji, Aswathy, Volmar, Claude-Henry, Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227815/
https://www.ncbi.nlm.nih.gov/pubmed/37253858
http://dx.doi.org/10.1038/s41573-023-00704-7