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Amplifying gene expression with RNA-targeted therapeutics
Many diseases are caused by insufficient expression of mutated genes and would benefit from increased expression of the corresponding protein. However, in drug development, it has been historically easier to develop drugs with inhibitory or antagonistic effects. Protein replacement and gene therapy...
Autores principales: | Khorkova, Olga, Stahl, Jack, Joji, Aswathy, Volmar, Claude-Henry, Wahlestedt, Claes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227815/ https://www.ncbi.nlm.nih.gov/pubmed/37253858 http://dx.doi.org/10.1038/s41573-023-00704-7 |
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