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The Emerging Landscape of Natural Small-molecule Therapeutics for Huntington’s Disease
Huntington’s disease (HD) is a rare and fatal neurodegenerative disorder with no disease-modifying therapeutics. HD is characterized by extensive neuronal loss and is caused by the inherited expansion of the huntingtin (HTT) gene that encodes a toxic mutant HTT (mHTT) protein having expanded polyglu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227909/ https://www.ncbi.nlm.nih.gov/pubmed/36797612 http://dx.doi.org/10.2174/1570159X21666230216104621 |