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The Emerging Landscape of Natural Small-molecule Therapeutics for Huntington’s Disease

Huntington’s disease (HD) is a rare and fatal neurodegenerative disorder with no disease-modifying therapeutics. HD is characterized by extensive neuronal loss and is caused by the inherited expansion of the huntingtin (HTT) gene that encodes a toxic mutant HTT (mHTT) protein having expanded polyglu...

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Detalles Bibliográficos
Autores principales: Bhat, Shahnawaz Ali, Ahamad, Shakir, Dar, Nawab John, Siddique, Yasir Hassan, Nazir, Aamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227909/
https://www.ncbi.nlm.nih.gov/pubmed/36797612
http://dx.doi.org/10.2174/1570159X21666230216104621