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Vitamin D receptor (VDR) on the cell membrane of mouse macrophages participates in the formation of lipopolysaccharide tolerance: mVDR is related to the effect of artesunate to reverse LPS tolerance

It is unclear whether membrane vitamin D receptor (mVDR) exists on the macrophage membrane or whether mVDR is associated with lipopolysaccharide (LPS) tolerance. Herein, we report that interfering with caveolae and caveolae-dependent lipid rafts inhibited the formation of LPS tolerance. VDR was dete...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhou, Jun, Hua, Ling, Li, Pan, Wu, Jiaqi, Shang, Shenglan, Deng, Fei, Luo, Jing, Liao, Mengling, Wang, Nuoyan, Pan, Xichun, Yuan, Yue, Zheng, Yue, Lu, Yonglin, Huang, Yasi, Zheng, Jiang, Liu, Xin, Li, Xiaoli, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227983/
https://www.ncbi.nlm.nih.gov/pubmed/37248534
http://dx.doi.org/10.1186/s12964-023-01137-w