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Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats through autophagy-mediated anti-senescent mechanism

BACKGROUND: Diabetic nephropathy (DN) is one of the most severe complications of diabetes mellitus, which is characterized by early occurrence of albuminuria and end-stage glomerulosclerosis. Senescence and autophagy of podocytes play an important role in DN development. Human umbilical cord-derived...

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Detalles Bibliográficos
Autores principales: Li, Xinyue, Guo, Le, Chen, Jingan, Liang, Haowei, Liu, Yi, Chen, Wei, Zhou, Li, Shan, Letian, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228071/
https://www.ncbi.nlm.nih.gov/pubmed/37248536
http://dx.doi.org/10.1186/s13287-023-03354-z