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Intravenous injection of human umbilical cord-derived mesenchymal stem cells ameliorates not only blood glucose but also nephrotic complication of diabetic rats through autophagy-mediated anti-senescent mechanism
BACKGROUND: Diabetic nephropathy (DN) is one of the most severe complications of diabetes mellitus, which is characterized by early occurrence of albuminuria and end-stage glomerulosclerosis. Senescence and autophagy of podocytes play an important role in DN development. Human umbilical cord-derived...
Autores principales: | Li, Xinyue, Guo, Le, Chen, Jingan, Liang, Haowei, Liu, Yi, Chen, Wei, Zhou, Li, Shan, Letian, Wang, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228071/ https://www.ncbi.nlm.nih.gov/pubmed/37248536 http://dx.doi.org/10.1186/s13287-023-03354-z |
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