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Validation of DREADD agonists and administration route in a murine model of sleep enhancement

BACKGROUND: Chemogenetics is a powerful tool to study the role of specific neuronal populations in physiology and diseases. Of particular interest, in mice, acute and specific activation of parafacial zone (PZ) GABAergic neurons expressing the Designer Receptors Activated by Designer Drugs (DREADD)...

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Detalles Bibliográficos
Autores principales: Ferrari, Loris L., Ogbeide-Latario, Oghomwen E., Gompf, Heinrich S., Anaclet, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228294/
https://www.ncbi.nlm.nih.gov/pubmed/35914577
http://dx.doi.org/10.1016/j.jneumeth.2022.109679