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Validation of DREADD agonists and administration route in a murine model of sleep enhancement
BACKGROUND: Chemogenetics is a powerful tool to study the role of specific neuronal populations in physiology and diseases. Of particular interest, in mice, acute and specific activation of parafacial zone (PZ) GABAergic neurons expressing the Designer Receptors Activated by Designer Drugs (DREADD)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228294/ https://www.ncbi.nlm.nih.gov/pubmed/35914577 http://dx.doi.org/10.1016/j.jneumeth.2022.109679 |