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Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase

Phenethyl-based edelfosine-analogs with saturated, monounsaturated, or polyunsaturated alkoxy substituents on phenyl ring were designed as novel antitumor lipids modulating p38 MAPK. Evaluation of the synthesised compounds against nine panels of diverse cancer cells presented saturated and monounsat...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed H. E., Oh, Yeon Il, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Alam, Md. Maqusood, Park, Sang-Eun, Chung, Kyung-Sook, Lee, Kyung-Tae, Lee, Yong Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228308/
https://www.ncbi.nlm.nih.gov/pubmed/37246947
http://dx.doi.org/10.1080/14756366.2023.2217695