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CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variants

The expression of viral antigens in chronic hepatitis B virus (HBV) infection drives continuous liver inflammation, one of the main risk factors to develop liver cancer. HBV developed immune-suppressive functions to escape from the host immune system, but their link to liver tumor development is not...

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Detalles Bibliográficos
Autores principales: Qiu, Na, Srikanth, Akshaya, Mulaw, Medhanie, Tharehalli, Umesh, Selvachandran, Shanthiya, Wagner, Martin, Seufferlein, Thomas, Stifter, Katja, Lechel, André, Schirmbeck, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228399/
https://www.ncbi.nlm.nih.gov/pubmed/37261086
http://dx.doi.org/10.1080/2162402X.2023.2215096