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CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variants
The expression of viral antigens in chronic hepatitis B virus (HBV) infection drives continuous liver inflammation, one of the main risk factors to develop liver cancer. HBV developed immune-suppressive functions to escape from the host immune system, but their link to liver tumor development is not...
Autores principales: | Qiu, Na, Srikanth, Akshaya, Mulaw, Medhanie, Tharehalli, Umesh, Selvachandran, Shanthiya, Wagner, Martin, Seufferlein, Thomas, Stifter, Katja, Lechel, André, Schirmbeck, Reinhold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228399/ https://www.ncbi.nlm.nih.gov/pubmed/37261086 http://dx.doi.org/10.1080/2162402X.2023.2215096 |
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