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Studying TIGIT activity against tumors through the generation of knockout mice
The use of antibodies to block inhibitory receptors, primarily anti-PD1 and CTLA4 (known as checkpoint therapy) revolutionized cancer treatment. However, despite these successes, the majority of cancer patients do not respond to the checkpoint treatment, emphasizing the need for development of addit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228407/ https://www.ncbi.nlm.nih.gov/pubmed/37261087 http://dx.doi.org/10.1080/2162402X.2023.2217735 |