Cargando…

METTL3-mediated m(6)A modification of lnc KCNQ1OT1 promotes doxorubicin resistance in breast cancer by regulating miR-103a-3p/MDR1 axis

Doxorubicin (DOX) resistance in breast cancer (BC) poses a huge challenge for the therapeutic effect on BC. Lnc KCNQ1OT1 play crucial roles in chemotherapy resistance. However, the role and mechanism of lnc KCNQ1OT1 in DOX resistance BC have not been investigated, which merits further exploration. B...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Zhiyang, Cao, Yukun, Yang, Yuan, Wang, Shouman, Chen, Feiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228414/
https://www.ncbi.nlm.nih.gov/pubmed/37243702
http://dx.doi.org/10.1080/15592294.2023.2217033