Hypothetical Estimands in Clinical Trials: A Unification of Causal Inference and Missing Data Methods

The ICH E9 addendum introduces the term intercurrent event to refer to events that happen after treatment initiation and that can either preclude observation of the outcome of interest or affect its interpretation. It proposes five strategies for handling intercurrent events to form an estimand but...

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Detalles Bibliográficos
Autores principales: Olarte Parra, Camila, Daniel, Rhian M., Bartlett, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228513/
https://www.ncbi.nlm.nih.gov/pubmed/37260584
http://dx.doi.org/10.1080/19466315.2022.2081599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228513/
https://www.ncbi.nlm.nih.gov/pubmed/37260584
http://dx.doi.org/10.1080/19466315.2022.2081599

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