Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants

Mutations that result in a mild impairment of mitochondrial function can extend longevity. Previous studies have shown that the increase in lifespan is dependent on stress responsive transcription factors, including DAF-16/FOXO, which exhibits increased nuclear localization in long-lived mitochondri...

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Detalles Bibliográficos
Autores principales: Traa, Annika, Shields, Hazel, AlOkda, Abdelrahman, Rudich, Zenith D., Ko, Bokang, Van Raamsdonk, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228650/
https://www.ncbi.nlm.nih.gov/pubmed/37261067
http://dx.doi.org/10.3389/fragi.2023.1145198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228650/
https://www.ncbi.nlm.nih.gov/pubmed/37261067
http://dx.doi.org/10.3389/fragi.2023.1145198

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