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Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants
Mutations that result in a mild impairment of mitochondrial function can extend longevity. Previous studies have shown that the increase in lifespan is dependent on stress responsive transcription factors, including DAF-16/FOXO, which exhibits increased nuclear localization in long-lived mitochondri...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228650/ https://www.ncbi.nlm.nih.gov/pubmed/37261067 http://dx.doi.org/10.3389/fragi.2023.1145198 |