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Bootstrap confidence for molecular evolutionary estimates from tumor bulk sequencing data

Bulk sequencing is commonly used to characterize the genetic diversity of cancer cell populations in tumors and the evolutionary relationships of cancer clones. However, bulk sequencing produces aggregate information on nucleotide variants and their sample frequencies, necessitating computational me...

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Detalles Bibliográficos
Autores principales: Huzar, Jared, Shenoy, Madelyn, Sanderford, Maxwell D., Kumar, Sudhir, Miura, Sayaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228696/
https://www.ncbi.nlm.nih.gov/pubmed/37261293
http://dx.doi.org/10.3389/fbinf.2023.1090730