Cargando…

Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expression

Intermittent hypoxia (IH) is a major clinical feature of obstructive sleep apnea (OSA). The mechanisms that become dysregulated after periods of exposure to IH are unclear, particularly in the early stages of disease. The circadian clock governs a wide array of biological functions and is intimately...

Descripción completa

Detalles Bibliográficos
Autores principales: Koritala, Bala S. C., Lee, Yin Yeng, Gaspar, Laetitia S., Bhadri, Shweta S., Su, Wen, Wu, Gang, Francey, Lauren J., Ruben, Marc D., Gong, Ming C., Hogenesch, John B., Smith, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10228805/
https://www.ncbi.nlm.nih.gov/pubmed/37252926
http://dx.doi.org/10.1371/journal.pbio.3002139