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Theta/gamma Co-modulation Disruption After NMDAr Blockade by MK-801 Is Associated with Spatial Working Memory Deficits in Mice

Abnormal N-methyl-D-aspartate receptor (NMDAr) function has been linked to oscillopathies, psychosis, and cognitive dysfunction in schizophrenia (SCZ). Here, we investigate the role of NMDAr hypofunction in pathological oscillations and behavior. We implanted mice with tetrodes in the dorsal/interme...

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Detalles Bibliográficos
Autores principales: Abad-Perez, P., Molina-Payá, F.J., Martínez-Otero, L., Borrell, V., Redondo, R.L., Brotons-Mas, J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229075/
https://www.ncbi.nlm.nih.gov/pubmed/36990270
http://dx.doi.org/10.1016/j.neuroscience.2023.03.022