Cargando…

Aging affects GABAergic function and calcium homeostasis in the mammalian central clock

INTRODUCTION: Aging impairs the function of the central circadian clock in mammals, the suprachiasmatic nucleus (SCN), leading to a reduction in the output signal. The weaker timing signal from the SCN results in a decline in rhythm strength in many physiological functions, including sleep–wake patt...

Descripción completa

Detalles Bibliográficos
Autores principales: Olde Engberink, Anneke H. O., de Torres Gutiérrez, Pablo, Chiosso, Anna, Das, Ankita, Meijer, Johanna H., Michel, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229097/
https://www.ncbi.nlm.nih.gov/pubmed/37260848
http://dx.doi.org/10.3389/fnins.2023.1178457