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Aging affects GABAergic function and calcium homeostasis in the mammalian central clock
INTRODUCTION: Aging impairs the function of the central circadian clock in mammals, the suprachiasmatic nucleus (SCN), leading to a reduction in the output signal. The weaker timing signal from the SCN results in a decline in rhythm strength in many physiological functions, including sleep–wake patt...
Autores principales: | Olde Engberink, Anneke H. O., de Torres Gutiérrez, Pablo, Chiosso, Anna, Das, Ankita, Meijer, Johanna H., Michel, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229097/ https://www.ncbi.nlm.nih.gov/pubmed/37260848 http://dx.doi.org/10.3389/fnins.2023.1178457 |
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