Hypermetabolism in mice carrying a near-complete human chromosome 21

Mostrar otras versiones (1)

The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning the impact of aneuploidy on systemic metabolism using a non-mosaic transchromosomic mouse model (TcM...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarver, Dylan C, Xu, Cheng, Rodriguez, Susana, Aja, Susan, Jaffe, Andrew E, Gao, Feng J, Delannoy, Michael, Periasamy, Muthu, Kazuki, Yasuhiro, Oshimura, Mitsuo, Reeves, Roger H, Wong, G William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229126/
https://www.ncbi.nlm.nih.gov/pubmed/37249575
http://dx.doi.org/10.7554/eLife.86023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229126/
https://www.ncbi.nlm.nih.gov/pubmed/37249575
http://dx.doi.org/10.7554/eLife.86023

Ejemplares similares