Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents

Adeno-associated viruses (AAVs) are one of the most promising tools for gene therapy applications. These vectors are purified using affinity and ion exchange chromatography, typically using packed beds of resin adsorbents. This leads to diffusion and pressure drop limitations that affect process pro...

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Detalles Bibliográficos
Autores principales: Neto, Salomé, Mendes, João P., Santos, Susana B. Dos, Solbrand, Anita, Carrondo, Manuel J. T., Peixoto, Cristina, Silva, Ricardo J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229133/
https://www.ncbi.nlm.nih.gov/pubmed/37260828
http://dx.doi.org/10.3389/fbioe.2023.1183974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229133/
https://www.ncbi.nlm.nih.gov/pubmed/37260828
http://dx.doi.org/10.3389/fbioe.2023.1183974

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