Structural insights into a regulatory mechanism of FIR RRM1–FUSE interaction

FUBP-interacting repressor (FIR) is a suppressor of transcription of the proto-oncogene MYC. FIR binds to the far upstream element (FUSE) of the MYC promoter. Competition of FIR with FUSE-binding protein 1 (FUBP1) is a key mechanism of MYC transcriptional regulation. To gain insights into the struct...

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Detalles Bibliográficos
Autores principales: Ni, Xiaomin, Joerger, Andreas C., Chaikuad, Apirat, Knapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229228/
https://www.ncbi.nlm.nih.gov/pubmed/37253421
http://dx.doi.org/10.1098/rsob.230031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229228/
https://www.ncbi.nlm.nih.gov/pubmed/37253421
http://dx.doi.org/10.1098/rsob.230031

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