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Mechanism of NURP1 in temozolomide resistance in hypoxia-treated glioma cells via the KDM3A/TFEB axis

Temozolomide (TMZ) resistance is a major obstacle in glioma treatment. Nuclear protein-1 (NUPR1) is a regulator of glioma progression. This study investigated the mechanism of NUPR1 in TMZ resistance in hypoxia-treated glioma cells and its mechanism in modulating autophagy. We treated TMZ-resistant...

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Detalles Bibliográficos
Autores principales: LI, TAO, FU, XIN, WANG, JIE, SHANG, WEI, WANG, XIAOTONG, ZHANG, LINYUN, LI, JUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229302/
https://www.ncbi.nlm.nih.gov/pubmed/37305393
http://dx.doi.org/10.32604/or.2023.028724