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Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

Glucose is vital for life, serving as both a source of energy and carbon building block for growth. When glucose is limiting, alternative nutrients must be harnessed. To identify mechanisms by which cells can tolerate complete loss of glucose, we performed nutrient-sensitized genome-wide genetic scr...

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Detalles Bibliográficos
Autores principales: Skinner, Owen S., Blanco-Fernández, Joan, Goodman, Russell P., Kawakami, Akinori, Shen, Hongying, Kemény, Lajos V., Joesch-Cohen, Lena, Rees, Matthew G., Roth, Jennifer A., Fisher, David E., Mootha, Vamsi K., Jourdain, Alexis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229423/
https://www.ncbi.nlm.nih.gov/pubmed/37198474
http://dx.doi.org/10.1038/s42255-023-00774-2